![]() Focal rhabdomyosarcomatous, chondrosarcomatous, and liposarcomatous differentiation was observed. A common histologic feature was the presence of small, primitive cells with blastematous qualities separated by an uncommitted stroma. These neoplasms were intrapulmonary, mediastinal, or pleural-based masses. The authors studied 11 pediatric intrathoracic neoplasms that share clinicopathologic features and constitute a specific tumor in children. Pleuropulmonary blastoma is a very rare childhood cancer that needs to be kept in mind in the pathological differential diagnosis of thoracic tumors in the children. The patient was treated with chemotherapy and showed no signs of recurrence in the follow-up of 9 months. The surgically sampled adjacent diafragma was also infiltrated with the tumor. Histological diagnosis was pleuropulmonary blastoma type 3. ![]() Immunohistochemical staining of the tumor cells were positive with vimentin and desmin. The tumor was composed of predominantly solid areas consisting blastemal cells with spindle, polygonal and round nuclei in the myxoid stroma. Biopsy and surgical material were examined histopathologically. The patient underwent core needle biopsy, wedge biopsy and lobectomy. ![]() Radiological examination revealed a solid mass filling the right hemithorax. A three-year-old boy presented with fever showed signs of upper respiratory tract infection. We present this entity which has no systematic data associated with its incidence in order to discuss clinical, histopathological, immunohistochemical features and the differential diagnosis. Pleuropulmonary blastoma is rare embryonal tumor of infancy and early childhood and it often arises from lung and more rarely from the parietal pleura.
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